Monday, 18 Feb 2019

Pregnenolone – A Steroid Hormone

Pregnenolone – A Steroid Hormone
Pregnenolone is an endogenous steroid hormone. It acts as a neurosteroid. It has many powerful nootropic gains. It is synthesized from cholesterol. In this synthesis radiolabelled cholesterol is used.
Pregnenolone is very effective as an energy pill. Nowadays it’s been used as focus booster and mood enhancer as well. Modern science has proved that pregnenolone can also be used in the improvement of comprehension, critical analysis, information processing and as a memory enhancer.
Few studies state that this is the most effective memory enhancer which is reported till date. Pregnenolone is responsible for synthesis of many chemicals and few hormones in the body like estrogens, androgens and glucocorticoids.
Pregnenolone is a steroidal hormone. Synthesis of pregnenolone happens mainly in the adrenal glands from cholesterol. It also occurs even in liver, brain, testicles, skin, ovaries and retinas. When taken as a steroid, pregnenolone works as a precursor to progesterone, estrogen, testosterone and cortisol. Pregnenolone is considered as a pro-hormone. It is called so because it is responsible for the synthesis of other chemicals and hormones. This is said produce very less, negligible side effects and very little androgenic, estrogenic and anabolic activity.
Research conducted on pregnenolone in around 1940’s realized the use of pregnenolone as a supplement. They showed that this can be used in the individuals who are fatigued and who are under stress. Meantime one more very effective steroid came to limelight called cortisol. So, pregnenolone didn’t get much attention from modern science.
It can be used in the deficient individuals as a brain enhancer.
Many experience rise in energy levels, vision memory and clarity of thinking by using pregnenolone.
For some people it acts as a mood enhancer in sexual enjoyment or libido and wellbeing.
In general people use for pregnenolone as a memory booster. It is been observed that levels of acetylcholine in many regions of the brain including hippocampus will increase by the intake of pregnenolone. This really helps in the improvement of memory.
In women it can reduce the premenstrual symptoms and hot flashes.
The major reason why people are behind pregnenolone is that treatments like hormone therapy can be done by using very small doses. This is safe as well as it improves energy, visual clarity and sexual pleasure in the individual.
As long as people take it in considerable quantity there will not be any side effects. But if it is taken in more quantity chances are there that it could cause some side effects.
Pregnenolone is very effective in the treatment of rheumatoid arthritis. Dosage suggested for this treatment is 300mg per day. If this followed for 40 days, there will be significant reduction in joint pain. It improves strength and range of motion by reducing tenderness and spasticity. Again results depend on individual. For some individual there may be very less improvements. But when cortisol came into industry, which was very effective in treating arthritis, pregnenolone went into back stage. But cortisol has many side effects which the modern science is revealing today. Still the medical industry is not much interested towards pregnenolone because it is a natural hormone and cannot be patented.